For Biology Professor, Cutting Edge Research ‘A Team Effort’

February 19th, 2014 by 

Photo by: John Buckingham

Robert Bellin, associate professor of biology at Holy Cross, is currently researching the causes of neurofibromatosis type-2 in a laboratory setting with his junior and senior students, a project he refers to as “a team effort.”

Bellin became interested in neurofibromatosis during a post-doctoral position at Boston Children’s Hospital after earning his Ph.D. in biochemistry from Iowa State University. He has conducted research on the disorder for 14 years.

Neurofibromatosis, also known as NF, refers to a broad range of inherited gene diseases that cause tumorous growths in different regions of the body. NF affects approximately 150,000 people worldwide.

Bellin’s research focuses specifically on NF Type-2 (NF-2), a form of the disease which causes non-malignant brain tumors that impair audio-visual perception. His studies focus on a protein within NF-2 cells called “merlin.” The exact nature of this gene is not entirely understood, but mutations of it are what seem to result in NF-2.

This is not Bellin’s only research project. In fact, he’s working on five more. With so many plates spinning in the air, he relies on his junior and senior students to carry some of the load. Much of the work into NF-2, “is done by my upper-level biology students,” he says. “They’ve been the ones who have often made some of the most significant developments.” The three most recent students to work with Bellin on the NF-2 project are Cat Flynn ’12, Mary Zabinski ’13 and, currently, Roy Gildersleeve ’14, all biology majors.

Flynn was involved in creating mutant forms of the merlin protein that match those in the human NF2 patient database, Zabinski tested those proteins by cell culture and confocal microscopy, and Gildersleeve is using those mutant forms of merlin to generate permanent cell-based models of NF2 in cell culture, which future students in the lab will use for continued studies.

With the support of a scientific grant from the school to fund their research, Bellin and his team have advanced their research for many years in a row, and are looking to sustain that momentum. While Bellin says that he’s, “not likely to find a cure or new treatment,” he hopes his team is able to make valuable contributions to the scientific community’s ongoing NF-2 research efforts.

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Tickets for Alternate College Theatre Production of "Stop Kiss"
11/21/2017
Theatre
Henry M. Hogan Campus Center Lobby Table 1
Buy tickets for “Stop Kiss,” the Alternate College...
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Tickets for Alternate College Theatre Production of "Stop Kiss"
11/21/2017
Theatre
Henry M. Hogan Campus Center Lobby Table 1
Buy tickets for “Stop Kiss,” the Alternate College...
See More >>


Open Enrollment Assistance
11/21/2017
Human Resources
Henry M. Hogan Campus Center 410 - Computer Lab
Open to Campus Community Only
See More >>


Rethinking the Afropolitan: Photographs by Héctor Mediavilla and Christopher López
11/21/2017
Iris and B. Gerald Cantor Art Gallery
O'Kane Hall Cantor Art Gallery
“Making Visual the Music of Ismael Rivera” | Photographs...
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COES Sales Club Meetings
11/23/2017
COES Professional Program & Prebusiness Program
Edith Stein Hall 118C
Explore the sales and management industries of business and gain the tools to...
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COES HC Capital Club Meeting
11/27/2017
COES Professional Program & Prebusiness Program
Edith Stein Hall 216
HC Capital seeks to supplement the liberal arts by providing the technical skills...
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Rethinking the Afropolitan: Photographs by Héctor Mediavilla and Christopher López
11/27/2017
Iris and B. Gerald Cantor Art Gallery
O'Kane Hall Cantor Art Gallery
“Making Visual the Music of Ismael Rivera” | Photographs...
See More >>


COES Finance Club Meetings
11/28/2017
COES Professional Program & Prebusiness Program
Edith Stein Hall 216
The Finance Club offers students the opportunity to gain a stronger understanding...
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Study Smarter, Not Harder!
11/28/2017
Academic Services and Learning Resources
Henry M. Hogan Campus Center 408(09)
Why is it so hard to remember what you just heard in lecture or...
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Rethinking the Afropolitan: Photographs by Héctor Mediavilla and Christopher López
11/28/2017
Iris and B. Gerald Cantor Art Gallery
O'Kane Hall Cantor Art Gallery
“Making Visual the Music of Ismael Rivera” | Photographs...
See More >>


Women in Finance Forum
11/29/2017
COES Professional Program & Prebusiness Program
Edith Stein Hall 215
Open to the Public
See More >>


COES HCEG Meeting
11/29/2017
COES Professional Program & Prebusiness Program
Henry M. Hogan Campus Center 402(03)
HCEG (Holy Cross Entrepreneurs Group) is the student chapter of...
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Rethinking the Afropolitan: Photographs by Héctor Mediavilla and Christopher López
11/29/2017
Iris and B. Gerald Cantor Art Gallery
O'Kane Hall Cantor Art Gallery
“Making Visual the Music of Ismael Rivera” | Photographs...
See More >>


Alternate College Theatre Production: "Stop Kiss"
11/30/2017
Theatre
ers growing up and leaving their twenties behind. Callie and Sara meet in New York City at the turn of the millennium. Sara wants to change the world; Callie simply wants to get by. They could be best of friends or even something more – if only they could make a decision. But making that decision isn’t easy and may even cause dangerous repercussions. An Alternate College Theatre production directed by Alexis Rappaport ’19. Tickets
ers growing up and leaving their twenties behind. Callie and Sara meet in New York City at the turn of...
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BSU Fashion Show Practice
11/30/2017
Office of Multicultural Education
Henry M. Hogan Campus Center 320
Open to Campus Community Only
See More >>


COES Sales Club Meetings
11/30/2017
COES Professional Program & Prebusiness Program
Edith Stein Hall 118C
Explore the sales and management industries of business and gain the tools to...
See More >>


City Year Info Table
11/30/2017
Center for Career Development
Henry M. Hogan Campus Center Lobby Table 3
Open to Campus Community Only
See More >>


Rethinking the Afropolitan: Photographs by Héctor Mediavilla and Christopher López
11/30/2017
Iris and B. Gerald Cantor Art Gallery
O'Kane Hall Cantor Art Gallery
“Making Visual the Music of Ismael Rivera” | Photographs...
See More >>


Alternate College Theatre Production: "Stop Kiss"
12/1/2017
Theatre
ers growing up and leaving their twenties behind. Callie and Sara meet in New York City at the turn of the millennium. Sara wants to change the world; Callie simply wants to get by. They could be best of friends or even something more – if only they could make a decision. But making that decision isn’t easy and may even cause dangerous repercussions. An Alternate College Theatre production directed by Alexis Rappaport ’19. Tickets
ers growing up and leaving their twenties behind. Callie and Sara meet in New York City at the turn of...
See More >>


Lecture: Quayshawn Spencer on a Radical Solution to the Race Problem
12/1/2017
Philosophy
Carol and Park B. Smith Hall Rehm Lib
Quayshawn Spencer, assistant professor of philosophy at the University...
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Rethinking the Afropolitan: Photographs by Héctor Mediavilla and Christopher López
12/1/2017
Iris and B. Gerald Cantor Art Gallery
O'Kane Hall Cantor Art Gallery
“Making Visual the Music of Ismael Rivera” | Photographs...
See More >>


Alternate College Theatre Production: "Stop Kiss"
12/2/2017
Theatre
ers growing up and leaving their twenties behind. Callie and Sara meet in New York City at the turn of the millennium. Sara wants to change the world; Callie simply wants to get by. They could be best of friends or even something more – if only they could make a decision. But making that decision isn’t easy and may even cause dangerous repercussions. An Alternate College Theatre production directed by Alexis Rappaport ’19. Tickets
ers growing up and leaving their twenties behind. Callie and Sara meet in New York City at the turn of...
See More >>


Alternate College Theatre Production: "Stop Kiss"
12/2/2017
Theatre
Fenwick Theatre
“Stop Kiss,” an Alternate College Theatre production, is being staged on...
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Rethinking the Afropolitan: Photographs by Héctor Mediavilla and Christopher López
12/2/2017
Iris and B. Gerald Cantor Art Gallery Open to the Public
O'Kane Hall Cantor Art Gallery
“Making Visual the Music of Ismael Rivera” | Photographs...
See More >>


Alternate College Theatre Production: "Stop Kiss"
12/3/2017
Theatre
Fenwick Theatre
“Stop Kiss,” an Alternate College Theatre production, is being staged on...
See More >>


COES HC Capital Club Meeting
12/4/2017
COES Professional Program & Prebusiness Program
Edith Stein Hall 216
HC Capital seeks to supplement the liberal arts by providing the technical skills...
See More >>


Rethinking the Afropolitan: Photographs by Héctor Mediavilla and Christopher López
12/4/2017
Iris and B. Gerald Cantor Art Gallery
O'Kane Hall Cantor Art Gallery
“Making Visual the Music of Ismael Rivera” | Photographs...
See More >>


COES Finance Club Meetings
12/5/2017
COES Professional Program & Prebusiness Program
Edith Stein Hall 216
The Finance Club offers students the opportunity to gain a stronger understanding...
See More >>


Rethinking the Afropolitan: Photographs by Héctor Mediavilla and Christopher López
12/5/2017
Iris and B. Gerald Cantor Art Gallery
O'Kane Hall Cantor Art Gallery
“Making Visual the Music of Ismael Rivera” | Photographs...
See More >>


Women in Finance Forum
12/6/2017
COES Professional Program & Prebusiness Program
Edith Stein Hall 215
Open to the Public
See More >>


Prof. Sheehy - Virology Poster Presentations
12/6/2017
Biochemistry
Smith Laboratories SPILLANE
Open to Campus Community Only
See More >>


COES HCEG Meeting
12/6/2017
COES Professional Program & Prebusiness Program
Henry M. Hogan Campus Center 304(05)
HCEG (Holy Cross Entrepreneurs Group) is the student chapter of...
See More >>


Rethinking the Afropolitan: Photographs by Héctor Mediavilla and Christopher López
12/6/2017
Iris and B. Gerald Cantor Art Gallery
O'Kane Hall Cantor Art Gallery
“Making Visual the Music of Ismael Rivera” | Photographs...
See More >>


BSU Fashion Show Practice
12/7/2017
Office of Multicultural Education
Henry M. Hogan Campus Center 408(09)
Open to Campus Community Only
See More >>


COES Sales Club Meetings
12/7/2017
COES Professional Program & Prebusiness Program
Edith Stein Hall 118C
Explore the sales and management industries of business and gain the tools to...
See More >>


Rethinking the Afropolitan: Photographs by Héctor Mediavilla and Christopher López
12/7/2017
Iris and B. Gerald Cantor Art Gallery
O'Kane Hall Cantor Art Gallery
“Making Visual the Music of Ismael Rivera” | Photographs...
See More >>


Rethinking the Afropolitan: Photographs by Héctor Mediavilla and Christopher López
12/8/2017
Iris and B. Gerald Cantor Art Gallery
O'Kane Hall Cantor Art Gallery
“Making Visual the Music of Ismael Rivera” | Photographs...
See More >>


Rethinking the Afropolitan: Photographs by Héctor Mediavilla and Christopher López
12/9/2017
Iris and B. Gerald Cantor Art Gallery Open to the Public
O'Kane Hall Cantor Art Gallery
“Making Visual the Music of Ismael Rivera” | Photographs...
See More >>


Rethinking the Afropolitan: Photographs by Héctor Mediavilla and Christopher López
12/11/2017
Iris and B. Gerald Cantor Art Gallery
O'Kane Hall Cantor Art Gallery
“Making Visual the Music of Ismael Rivera” | Photographs...
See More >>


Rethinking the Afropolitan: Photographs by Héctor Mediavilla and Christopher López
12/12/2017
Iris and B. Gerald Cantor Art Gallery
O'Kane Hall Cantor Art Gallery
“Making Visual the Music of Ismael Rivera” | Photographs...
See More >>


Rethinking the Afropolitan: Photographs by Héctor Mediavilla and Christopher López
12/13/2017
Iris and B. Gerald Cantor Art Gallery
O'Kane Hall Cantor Art Gallery
“Making Visual the Music of Ismael Rivera” | Photographs...
See More >>


Rethinking the Afropolitan: Photographs by Héctor Mediavilla and Christopher López
12/14/2017
Iris and B. Gerald Cantor Art Gallery
O'Kane Hall Cantor Art Gallery
“Making Visual the Music of Ismael Rivera” | Photographs...
See More >>


Rethinking the Afropolitan: Photographs by Héctor Mediavilla and Christopher López
12/15/2017
Iris and B. Gerald Cantor Art Gallery
O'Kane Hall Cantor Art Gallery
“Making Visual the Music of Ismael Rivera” | Photographs...
See More >>


Sam's Club Information
1/10/2018
Human Resources
Henry M. Hogan Campus Center Lobby Table 1
Open to Campus Community Only
See More >>


Non-Profit Careers Conference
1/16/2018
Community Based Learning
Carol and Park B. Smith Hall Rehm Lib
The annual Non-Profit Careers Conference is held in January for...
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Non-Profit Careers Conference
1/17/2018
Community Based Learning
Carol and Park B. Smith Hall Rehm Lib
The annual Non-Profit Careers Conference is held in January for...
See More >>


Male Involvement Coalition (MIC)
1/29/2018
Office of Multicultural Education
Henry M. Hogan Campus Center 320
Open to Campus Community Only
See More >>


BSU Gathering
2/6/2018
Office of Multicultural Education
Henry M. Hogan Campus Center Suite B/C - 4th Fl
Open to Campus Community Only
See More >>


Sam's Club Information
2/8/2018
Human Resources
Henry M. Hogan Campus Center Lobby Table 1
Open to Campus Community Only
See More >>

See All