Intro to Neuroscience: New Course Offers Innovative, Integrative Exploration of the Brain

Along with the course, a new interdisciplinary minor challenges students at the intersection of psychology, biology, chemistry, mathematics and physics
January 15th, 2018 by 

Alo Basu lectures as students inspect models of the brain.
Alo Basu lectures as students inspect models of the brain. Photo by Tom Rettig

Neuroscience is a field that requires its scientists to integrate knowledge and thinking from many disciplines. Holy Cross has a long history of offering elective courses related to neuroscience, but with the establishment of a new interdisciplinary minor in the field, a team of Holy Cross professors led by Alo Basu, associate professor of psychology, sought to create a fundamental course that offered an innovative, integrative academic experience for students.

Basu’s curriculum development team included David Damiano, professor of mathematics; Andre Isaacs, assistant professor of chemistry; Michelle Mondoux, associate professor of biology; Tomohiko Narita, associate professor and chair of physics; and Constance Royden, professor of computer science and computer science coordinator. With funding from a spring 2016 Hewlett-Mellon grant, Basu and her colleagues created a rigorous course rooted in STEM concepts by using a “flipped” classroom model that challenges students to come prepared to push their thinking in class.

The course, offered during the fall semester, is mainly targeted to first-years. It is thoughtfully designed to provide an early entry point for students, many of whom may be new to the sciences, to explore neuroscience and to gain an appreciation for the complexity of the issues the field tackles and the diversity of methodologies used. For Basu, it is important that students understand how much faculty members from different departments contributed to the creation of this course because it removes a sense of “foreignness” for students when they are considering studying other disciplines.

On the day HCM visited class, the power and magic of the human brain was on full display: both on the colorful slides Basu presented of neurons, but perhaps more importantly in the impressive performance from her students, who drew on previously studied material to think through complex novel problems masterfully thrown at them at lightning speed.

This particular “flipped” class asked students to show up having studied a video and animations of how DNA is transcribed to RNA and how RNA is translated to protein. After a warm-up in which Basu elicited input from students to create a chalkboard visual of the components of a chemical synapse, students were shown actual images of neurons taken by researchers.

Basu asked students to think through how these researchers would go about determining which neurons release serotonin from their presynaptic terminals. She encouraged students to brainstorm in small teams before working through ideas as a group. They followed this model to explore various complex questions.

Alumna Victoria Mousley ’17, a psychology and deaf studies double major, with a concentration in gender, sexuality, and women’s studies, who is pursuing a career in cognitive neuroscience, saw the benefit of the course’s integrative approach when auditing the class in 2016: “I never fully understood how physics, math, biology and chemistry could attack the same questions about the brain I was asking in psychology. By introducing students to STEM topics, this course allows beginners to understand neuroscience as the expansive subject it is. In doing so, students can decide what they like and don’t like about all the different levels of analysis.”

Basu’s hope is that this course will serve as that launching pad for students to determine how the sciences and the field of neuroscience may fit into their Holy Cross education. The course has already attracted diverse minds, including music and computer science majors, and Basu expects to see that trend continue — something the field of neuroscience could use.

“There are pressing social needs to do with neurological and neuropsychiatric disorders that are affecting an increasing proportion of the world’s population,” says Basu. “The study of neuroscience offers a perspective on life and human nature that seeks to integrate many different domains of human knowledge; it prompts us to ask very large questions about who we are and our relationship to the natural world. It motivates us to think and work in inventive ways that challenge traditional boundaries between disciplines, and it trains us to be integrative thinkers by virtue of the complexity of the problems.”

Course Catalog

CISS 110: Introduction to Neuroscience

Professor: Alo Basu

Department: Center for Interdisciplinary Studies

Description: This course provides an integrative introduction to neuroscience through study of topics, including comparative vertebrate and invertebrate neuroanatomy, neurophysiology, sensory and motor systems, behavioral neurobiology, neuropharmacology and neural basis of cognition. In order to offer groundwork for continued interdisciplinary study of the neural basis of behavior, the course highlights fundamental principles of nervous system structure and function.

Meeting Times: Monday, Wednesday, Friday; 11–11:50 a.m.

Classroom: Swords 227

Flipped Class

Employing a “flipped” class model on selected days, this course requires students to spend significant time prior to class studying concepts related to biology, chemistry, physics, mathematics and neuroscience, some of which are covered in videos. They apply these concepts through problem sets and are expected to arrive to class prepared to extend their thinking to achieve a deeper understanding of nervous systems. Lab days are scheduled throughout the semester to provide opportunity for hands-on work.

Required Reading

  • “Neuroscience: Exploring the Brain” by Bear, Connors, and Paradiso, 4th ed.
  • Additional readings and videos assigned throughout the semester

Vocabulary

Integrative thinking = an approach that involves pulling together knowledge and tools from various disciplines and applying them

Assignments

  • Quizzes and four exams, including a final
  • Problem sets
  • Class participation

Grades: Problem sets, quizzes, exams and participation

Prerequisites: None, open to all students

About The Professor

Alo C. Basu is an associate professor in the Department of Psychology and currently serves as Neuroscience Advisor for students across the College. She earned her Ph.D. in neurobiology from Harvard University and has worked at Holy Cross for six years. Her fields of study include neurobiology of learning and memory, stress-related neuroplasticity, and genetic and environmental risk factors for neuropsychiatric disorders. Her recent scholarly work was published in “Behavioural Brain Research” and “Neurobiology of Learning and Memory.” A pedagogical article on the Introduction to Neuroscience course was recently published in the “Journal of Undergraduate Neuroscience Education” (2017 Volume 16: Issue 1); you can find it online at www.funjournal.org. She will be on sabbatical next year, which will include conducting research in the lab with students and working on course development. Basu was integral in establishing the new interdisciplinary minor in neuroscience at the College.


Written by Meredith Fidrocki for the Winter 2018 issue of Holy Cross Magazine.

About Holy Cross Magazine
Holy Cross Magazine (HCM) is the quarterly alumni publication of the College of the Holy Cross. The award-winning publication is mailed to alumni and friends of the College and includes intriguing profiles, make-you-think features, alumni news, exclusive photos and more. Visit magazine.holycross.edu/about to contact HCM, submit alumni class notes, milestones, or letters to the editor.

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Come to Feminist Forum's first meeting of the year, where we will be...
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"The Pursuit of Happiness: Black Women, Diasporic Dreams and the Politics of Emotional Transnationalism" A Lecture by Dr. Bianca Williams
10/31/2018
Africana Studies
Carol and Park B. Smith Hall Rehm Lib
Bianca C. Williams traces the experiences of African American...
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The Curious Incident of the Dog in the Night-Time
10/31/2018
Theatre
Henry M. Hogan Campus Center Lobby Table 1
LOBBY TABLEThe Curious Incident of the Dog in the Night-TimeBy...
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Holy Cross Chamber Players - Music of Francois Couperin
11/1/2018
Music
Brooks Music Center CONCERT HA
This concert is given in celebration of the 350th anniversary of the...
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The Curious Incident of the Dog in the Night-time
11/1/2018
Theatre
O'Kane Hall Fenwick Theatre
The Curious Incident of the Dog in the Night-TimeBy Simon Stephens, based...
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The Curious Incident of the Dog in the Night-Time
11/1/2018
Theatre
Henry M. Hogan Campus Center Lobby Table 1
LOBBY TABLEThe Curious Incident of the Dog in the Night-TimeBy...
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The Curious Incident of the Dog in the Night-time
11/2/2018
Theatre Open to the Public Categories: Theatre
O'Kane Hall Fenwick Theatre
The Curious Incident of the Dog in the Night-TimeBy Simon Stephens, based...
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The Curious Incident of the Dog in the Night-Time
11/2/2018
Theatre
Henry M. Hogan Campus Center Lobby Table 1
LOBBY TABLEThe Curious Incident of the Dog in the Night-TimeBy...
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The Curious Incident of the Dog in the Night-time
11/3/2018
Theatre Open to the Public Categories: Theatre
O'Kane Hall Fenwick Theatre
The Curious Incident of the Dog in the Night-TimeBy Simon Stephens, based...
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The Curious Incident of the Dog in the Night-Time
11/5/2018
Theatre
Henry M. Hogan Campus Center Lobby Table 2
LOBBY TABLEThe Curious Incident of the Dog in the Night-TimeBy...
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Assumption College Graduate Programs
11/5/2018
Center for Career Development
Henry M. Hogan Campus Center Lobby Table 1
Stop by the Assumption College Info Table to learn more about...
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The Curious Incident of the Dog in the Night-Time
11/6/2018
Theatre
Henry M. Hogan Campus Center Lobby Table 1
LOBBY TABLEThe Curious Incident of the Dog in the Night-TimeBy...
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Discussion: The Ethics and Economics of Legalized Sports Gambling
11/7/2018
McFarland Center for Religion
Carol and Park B. Smith Hall Rehm Lib
Following the Supreme Court decision in May to allow states to...
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The Curious Incident of the Dog in the Night-time
11/8/2018
Theatre Open to the Public Categories: Theatre
O'Kane Hall Fenwick Theatre
The Curious Incident of the Dog in the Night-TimeBy Simon Stephens, based...
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Eliot's 4 Quartets
11/8/2018
English
Carol and Park B. Smith Hall Rehm Lib
This is a rare opportunity to hear the entirety of Eliot's poetic...
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Kifle Wansamo, S.J. Lecture
11/8/2018
Africana Studies
Carol and Park B. Smith Hall Rehm Lib
Open to the Public
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BACAP Speaker - Philosophy Colloquium Event
11/8/2018
Philosophy
Carol and Park B. Smith Hall 501
Open to the Public
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BACAP Lecture/Philosophy Colloquium Series
11/8/2018
Philosophy
Carol and Park B. Smith Hall 201
Open to the Public
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The Curious Incident of the Dog in the Night-Time
11/8/2018
Theatre
Henry M. Hogan Campus Center Lobby Table 2
LOBBY TABLEThe Curious Incident of the Dog in the Night-TimeBy...
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The Curious Incident of the Dog in the Night-time
11/9/2018
Theatre Open to the Public Categories: Theatre
O'Kane Hall Fenwick Theatre
The Curious Incident of the Dog in the Night-TimeBy Simon Stephens, based...
See More >>


The Curious Incident of the Dog in the Night-Time
11/9/2018
Theatre
Henry M. Hogan Campus Center Lobby Table 1
LOBBY TABLEThe Curious Incident of the Dog in the Night-TimeBy...
See More >>


The Curious Incident of the Dog in the Night-time
11/10/2018
Theatre Open to the Public Categories: Theatre
O'Kane Hall Fenwick Theatre
The Curious Incident of the Dog in the Night-TimeBy Simon Stephens, based...
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Resume Writing Workshop with Deloitte and the Center for Career Dev.
11/13/2018
Center for Career Development
Henry M. Hogan Campus Center 320
Open to all students! Create a resume the write way!Come hear from...
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the little match girl passion
11/15/2018
Arts Transcending Borders (ATB)
O'Kane Hall Fenwick Theatre
In a brilliant theatrical adaptation with haunting shadow projections, masked...
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Lecture: Thomas White '69 in Defense of Dolphins
11/15/2018
McFarland Center for Religion
Carol and Park B. Smith Hall Rehm Lib
Thomas White, Holy Cross Class of 1969, will give a talk on "Dolphins,...
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the little match girl passion
11/16/2018
Arts Transcending Borders (ATB)
O'Kane Hall Fenwick Theatre
In a brilliant theatrical adaptation with haunting shadow projections, masked...
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Feminist Forum Weekly Meeting
11/28/2018
Diversity and Inclusion
Henry M. Hogan Campus Center 320
Come to Feminist Forum's first meeting of the year, where we will be...
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Lecture: Yale Theologian Willie Jennings on Race and Religion
11/28/2018
McFarland Center for Religion
Carol and Park B. Smith Hall Rehm Lib
Renowned American theologian Willie Jennings, associate professor...
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Sonita Sarker Lecture
11/29/2018
Gender
Carol and Park B. Smith Hall Rehm Lib
Open to the Public
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Concert Band - Dress Rehearsal
11/30/2018
Holy Cross Bands
Henry M. Hogan Campus Center Ballroom & 328
Open to Campus Community Only
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Athletics Workshop - Mindfulness
12/4/2018
Counseling Center
Henry M. Hogan Campus Center Ballroom & Dunn
Open to Campus Community Only
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City Year Info Table
12/4/2018
Center for Career Development
Henry M. Hogan Campus Center Lobby Table 1
Stop by the City Year Info Table to learn more about this...
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English Honors Midwinter Celebration
12/5/2018
English
Henry M. Hogan Campus Center Suite A - 4th Fl
Open to Campus Community Only
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MPE Meeting
1/28/2019
Office of Multicultural Education
Henry M. Hogan Campus Center 406(08)
Open to the Public
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Little Women: The Musical
1/28/2019
Theatre
Henry M. Hogan Campus Center Lobby Table 1
LOBBY TABLE - Little WomenBook by Allan Knee, based on the...
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Little Women: The Musical
1/29/2019
Theatre
Henry M. Hogan Campus Center Lobby Table 1
LOBBY TABLE - Little WomenBook by Allan Knee, based on the...
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Little Women: The Musical
1/30/2019
Theatre
Henry M. Hogan Campus Center Lobby Table 1
LOBBY TABLE - Little WomenBook by Allan Knee, based on the...
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Little Women
1/31/2019
Theatre
O'Kane Hall Fenwick Theatre
Little Women Book by Allan Knee, based on the novel by Louisa May AlcottMusic...
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Little Women: The Musical
1/31/2019
Theatre
Henry M. Hogan Campus Center Lobby Table 1
LOBBY TABLE - Little WomenBook by Allan Knee, based on the...
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Little Women
2/1/2019
Theatre
O'Kane Hall Fenwick Theatre
Little Women Book by Allan Knee, based on the novel by Louisa May AlcottMusic...
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Little Women
2/2/2019
Theatre
O'Kane Hall Fenwick Theatre
Little Women Book by Allan Knee, based on the novel by Louisa May AlcottMusic...
See More >>


Little Women
2/3/2019
Theatre
O'Kane Hall Fenwick Theatre
Little WomenBook by Allan Knee, based on the novel by Louisa May AlcottMusic...
See More >>


Little Women: The Musical
2/4/2019
Theatre
Henry M. Hogan Campus Center Lobby Table 1
LOBBY TABLE - Little WomenBook by Allan Knee, based on the...
See More >>


Little Women: The Musical
2/5/2019
Theatre
Henry M. Hogan Campus Center Lobby Table 1
LOBBY TABLE - Little WomenBook by Allan Knee, based on the...
See More >>


Little Women: The Musical
2/6/2019
Theatre
Henry M. Hogan Campus Center Lobby Table 1
LOBBY TABLE - Little WomenBook by Allan Knee, based on the...
See More >>


Little Women
2/7/2019
Theatre
O'Kane Hall Fenwick Theatre
Little Women Book by Allan Knee, based on the novel by Louisa May AlcottMusic...
See More >>


Little Women: The Musical
2/7/2019
Theatre
Henry M. Hogan Campus Center Lobby Table 1
LOBBY TABLE - Little WomenBook by Allan Knee, based on the...
See More >>


Little Women
2/8/2019
Theatre
O'Kane Hall Fenwick Theatre
Little Women Book by Allan Knee, based on the novel by Louisa May AlcottMusic...
See More >>


Little Women: The Musical
2/8/2019
Theatre
Henry M. Hogan Campus Center Lobby Table 1
LOBBY TABLE - Little WomenBook by Allan Knee, based on the...
See More >>


Little Women
2/9/2019
Theatre
O'Kane Hall Fenwick Theatre
Little Women Book by Allan Knee, based on the novel by Louisa May AlcottMusic...
See More >>


Little Women
2/10/2019
Theatre
O'Kane Hall Fenwick Theatre
Little WomenBook by Allan Knee, based on the novel by Louisa May AlcottMusic...
See More >>


MPE Meeting
2/11/2019
Office of Multicultural Education
Henry M. Hogan Campus Center 406(08)
Open to the Public
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MPE Meeting
2/25/2019
Office of Multicultural Education
Henry M. Hogan Campus Center 406(08)
Open to the Public
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Lecture: Samuel Moyn on the Christian Invention of Human Dignity
2/26/2019
McFarland Center for Religion
Carol and Park B. Smith Hall Rehm Lib
Open to the Public
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MPE Meeting
3/11/2019
Office of Multicultural Education
Henry M. Hogan Campus Center 304(05)
Open to Campus Community Only
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MPE Meeting
3/11/2019
Office of Multicultural Education
Henry M. Hogan Campus Center Suite B/C - 4th Fl
Open to the Public
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Organ concert - Benjamin Alard
3/17/2019
Music
St Joseph Memorial Chapel St Joseph Chapel
Benjamin Alard, OrganistChurch: Saint-Louis-en-Île,...
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MPE Meeting
3/25/2019
Office of Multicultural Education
Henry M. Hogan Campus Center Suite B/C - 4th Fl
Open to the Public
See More >>


MPE Meeting
3/25/2019
Office of Multicultural Education
Henry M. Hogan Campus Center 304(05)
Open to Campus Community Only
See More >>


Once in a Lifetime
4/1/2019
Theatre
Henry M. Hogan Campus Center Lobby Table 1
LOBBY TABLE - Once in a LifetimeBy George S. Kaufman and...
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Once in a Lifetime
4/2/2019
Theatre
Henry M. Hogan Campus Center Lobby Table 1
LOBBY TABLE - Once in a LifetimeBy George S. Kaufman and...
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Once in a Lifetime
4/3/2019
Theatre
Henry M. Hogan Campus Center Lobby Table 1
LOBBY TABLE - Once in a LifetimeBy George S. Kaufman and...
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Once in a Lifetime
4/4/2019
Theatre
O'Kane Hall Fenwick Theatre
Once in a Lifetime By George S. Kaufman and Moss HartApril 4-6 &...
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Once in a Lifetime
4/4/2019
Theatre
Henry M. Hogan Campus Center Lobby Table 1
LOBBY TABLE - Once in a LifetimeBy George S. Kaufman and...
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Once in a Lifetime
4/5/2019
Theatre
O'Kane Hall Fenwick Theatre
Once in a Lifetime By George S. Kaufman and Moss HartApril 4-6 &...
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Once in a Lifetime
4/5/2019
Theatre
Henry M. Hogan Campus Center Lobby Table 1
LOBBY TABLE - Once in a LifetimeBy George S. Kaufman and...
See More >>


Once in a Lifetime
4/6/2019
Theatre
O'Kane Hall Fenwick Theatre
Once in a Lifetime By George S. Kaufman and Moss HartApril 4-6 &...
See More >>


MPE Meeting
4/8/2019
Office of Multicultural Education
Henry M. Hogan Campus Center Suite B/C - 4th Fl
Open to the Public
See More >>


MPE Meeting
4/8/2019
Office of Multicultural Education
Henry M. Hogan Campus Center 304(05)
Open to Campus Community Only
See More >>


Once in a Lifetime
4/8/2019
Theatre
Henry M. Hogan Campus Center Lobby Table 2
LOBBY TABLE - Once in a LifetimeBy George S. Kaufman and...
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Once in a Lifetime
4/9/2019
Theatre
Henry M. Hogan Campus Center Lobby Table 2
LOBBY TABLE - Once in a LifetimeBy George S. Kaufman and...
See More >>


Once in a Lifetime
4/10/2019
Theatre
Henry M. Hogan Campus Center Lobby Table 2
LOBBY TABLE - Once in a LifetimeBy George S. Kaufman and...
See More >>


Once in a Lifetime
4/11/2019
Theatre
O'Kane Hall Fenwick Theatre
Once in a Lifetime By George S. Kaufman and Moss HartApril 4-6 &...
See More >>


Once in a Lifetime
4/11/2019
Theatre
Henry M. Hogan Campus Center Lobby Table 2
LOBBY TABLE - Once in a LifetimeBy George S. Kaufman and...
See More >>


Once in a Lifetime
4/12/2019
Theatre
O'Kane Hall Fenwick Theatre
Once in a Lifetime By George S. Kaufman and Moss HartApril 4-6 &...
See More >>


Once in a Lifetime
4/12/2019
Theatre
Henry M. Hogan Campus Center Lobby Table 2
LOBBY TABLE - Once in a LifetimeBy George S. Kaufman and...
See More >>


Once in a Lifetime
4/13/2019
Theatre
O'Kane Hall Fenwick Theatre
Once in a Lifetime By George S. Kaufman and Moss HartApril 4-6 &...
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Chapel Artist Series Organ Concert - Pavel Kohout
4/28/2019
Music
St Joseph Memorial Chapel St Joseph Chapel
Pavel Kohout, OrganistInternational Concert Organist, Prague,...
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MPE Meeting
4/29/2019
Office of Multicultural Education
Henry M. Hogan Campus Center 406(09)
Open to the Public
See More >>


Dance Concert
5/1/2019
Theatre
O'Kane Hall Fenwick Theatre
Dance ConcertMay 1 at 7:00 PM and 9:00 PMFenwick Theatre – 2nd...
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See All